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Scigress Explorer 7.5


  • New in the release:

    • New module MOS-F - MOS-F version 7.0 is a semi-empirical molecular orbital program that predicts spectroscopic properties of both open and closed-shell molecules. MOS-F extends the capabilities of Scigress beyond those provided by MOPAC and ZINDO.

    • New LocalSCF 2.0 - specifically designed for fast electronic structure calculations of very large, complex proteins. This latest version includes the following new features and enhancements:

      • New support for transition metals using d orbitals within the MNDO, AM1, PM3 and PM5 semi-empirical methods.

      • All atom quantum mechanical modeling of enzymes and DNA-transition metal complexes available for hundred thousand atom systems.

      • Energy calculations and geometry optimizations possible in gas- or solvated-phase.

      • Low resource requirements provided by using localized molecular orbitals for the protein and delocalized orbitals for the transition metal portion of the system.

      • New, computationally efficient, initial guess for the wave function of DNA/RNA systems.

      • New, reliable identification of structural errors in DNA/RNA structures.

      • New analytic energy gradient for improved geometry optimizations.

      • Support for transition metals using d orbital methods.

      • Faster local geometry optimizations in solvent environment.

      • New, improved initial guess generator.

      • More reliable SCF procedure.

      • Automatic control of memory consumption - orbital tidying.

      • A powerful Cartesian coordinate to PDB converter.

      • Bond order analysis for very large systems.

    • Scigress 7.5 restores the ability to use the same version of molecular mechanics that was available in Scigress 5.0. The MM2_V5 or MM3_V5 parameter set can be selected within Mechanics Setting dialog of the ProcedureEditor. This selection can be made for any experiment that uses Scigress Mechanics.