ADME DB is a database containing the latest and most comprehensive data on interactions of substances with Drug Metabolizing Enzymes and Drug Transporters. It is designed for use in drug research and development, including drug-drug interactions and ADME (Absorption, Distribution, Metabolism and Excretion) studies. The information is organized by category (therapeutic area), drug name, enzyme, reaction, and type. ADME DB is supported by chemical/metabolite structures as well as kinetic values found in the literature. The database is available online and completely searchable by keywords or chemical structures. Advanced searches are also available to support investigational studies on drug-drug interactions. The contents of the database were collected and organized in accordance with the original Human CYP and Transporter Metabolism Database as developed by Professor Slobodan Rendic (Zagreb, Croatia).
Contains more than 25 500 substances, a number of natural products and preparations, as well as other factors influencing Drug Metabolizing Enzymes activity.
Contains data collected from more than 10 300 citations.